Milk thistle extract
Milk thistle extract
Chardon-Marie (INCI: SILYBUM MARIANUM FRUIT EXTRACT) is an extract of Chardon-Marie (Fruit pulp, Extract (solvent extracted)). It is used as a skin care product.
Skin conditioningPrecautions for sensitive groups
Ingredient
Roles & functions
Skin conditioning — Keeps the skin in good condition and protects it; improves its comfort.
Dosage
Dosage guidance
oral
Single dose: 70 mg, 3 times daily
Source : Monograph (EMA/HMPC) — EMA/HMPC — Silybi mariani fructus · verified on July 20, 2026
General guidance for information only, ask a pharmacist about your situation.
Regulatory framework
What the authorities say
| Authority | Status |
|---|---|
| Commission européenne (CosIng, Règl. 1223/2009) | Autorisé |
| CLP classification (Reg. 1272/2008) | No CMR classification |
| ECHA — endocrine disruptor (human health) | Not identified as an endocrine disruptor |
| ECHA — Candidate List (SVHC, REACH Art. 59) | Not on the Candidate List (SVHC) |
| European Commission (Reg. 1223/2009, Annex III) | No cosmetic allergen subject to mandatory labelling |
| European Commission (EU catalogue of nanomaterials, Reg. 1223/2009) | No referenced nanoform |
Precautions
Who it is not recommended for
Safe to use during pregnancy?
Not recommended
En l’absence de données suffisantes, l’HMPC déconseille l’usage pendant la grossesse. À confirmer par le pharmacien.
Safe to use while breastfeeding?
Not recommended
En l’absence de données suffisantes, l’HMPC déconseille l’usage pendant l’allaitement. À confirmer par le pharmacien.
Suitable for children (under 12)?
Not recommended
L’HMPC ne recommande pas l’usage chez l’enfant de moins de 18 ans. À confirmer par le pharmacien.
Products
Products containing it
Laboratoire InolabOptiform Gluthation Réduit 98% Antioxydant Détox, 90 Gélules
AveneCleanance Comedomed 30ml
AveneAntirougeurs Rosamed Concentré Rougeurs Installées Peaux Sensibles, 30ml
AveneComedomed+ Soin Intensif Anti-Imperfections, 30ml
AveneCleanance Eau Micellaire, 400ml
AveneCleanance Gel Nettoyant, 100ml
AveneCleanance Gel Nettoyant, 200ml
AveneCleanance Gel Nettoyant Sans Savon, 400ml
DucrayNeoptide Sérum Antichute Et Croissance, 2X50ml
AveneCleanance Masque Détox, 50ml
Statistics
In Lou’s database
11
products listed
| Most frequent categories | Cleansers & makeup removers · Face · Anti-hair loss · Digestion & transit · Masks |
| Most frequent brands | Avene · Ducray · Laboratoire Inolab |
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This information is reported factually and with attribution (authorities and publications cited). It does not constitute medical advice, for your situation, ask a pharmacist or a healthcare professional for advice.
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