Nematode RH-polypeptide-47
Nematode RH-polypeptide-47
Synthetic polypeptide inspired by nematode proteins, used in cosmetics for its emollient and humectant properties. It helps maintain skin hydration by retaining water and softening the epidermis.
Skin conditioningEmollientProhibited in the EU
Ingredient
Roles & functions
Skin conditioning — Keeps the skin in good condition and protects it; improves its comfort.
Emollient — Softens and smooths the skin while limiting water loss.
Humectant — Attracts and retains water to help maintain hydration.
Regulatory framework
What the authorities say
| Authority | Status |
|---|---|
| Commission européenne (CosIng, Règl. 1223/2009) | Interdit (Annexe II) — Cells, tissues or products of human origin |
| CLP classification (Reg. 1272/2008) | No CMR classification |
| ECHA — endocrine disruptor (human health) | Not identified as an endocrine disruptor |
| ECHA — Candidate List (SVHC, REACH Art. 59) | Not on the Candidate List (SVHC) |
| European Commission (Reg. 1223/2009, Annex III) | No cosmetic allergen subject to mandatory labelling |
| European Commission (EU catalogue of nanomaterials, Reg. 1223/2009) | No referenced nanoform |
| European Commission — Annex II (Reg. 1223/2009) — maj Fri, 07 Aug 2026 16:37:22 GMT | Prohibited in cosmetics (Annex II) — Cells, tissues or products of human origin — Annexe II, entrée 416 |
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This information is reported factually and with attribution (authorities and publications cited). It does not constitute medical advice, for your situation, ask a pharmacist or a healthcare professional for advice.
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